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5 Days of Stem Cells
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Ernesto Goulart

Human Genome and Stem Cell Research Center, University of Sao Paulo – Brazil

Dr. Ernesto Goulart is a Post-Doctoral Fellow at the Human Genome and Stem Cell Research Center (University of Sao Paulo – Brazil) at Prof. Dr. Mayana Zatz’s lab. He is working for the last 7 years using induced pluripotent stem cells (iPS) differentiated cells in combination with several liver tissue engineering technologies and genetic engineering strategies in order to increase organ availability for transplant. Dr. Goulart has a PhD in Genetics by the University in Sao Paulo and was trained in Bioengineering at Temple University in Dr. Peter I. Lelkes’s lab.  

Using iPS-derived cells to generate a functional human liver through 3D bioprinting

Abstract:

Using iPS-derived cells in combination with tissue engineering strategies can lead the development of biofabricated functional autologous grafts for human transplant. To reach such goals it is fundamental to stablish robust and scalable iPS differentiation protocols with validated cell culture quality control and cellular phenotype functionality assessment. Finally, biomaterial and tissue performance must be optimized. In this presentation, Dr. Ernesto Goulart will show us how he and his team were able to generate a 3D bioprinted whole iPS-derived functional “mini-liver”.